Endocrine Abstracts

Introduction: Hepatic metabolism of inhaled corticosteroids (ICS) takes place via cytochrome P450 3A4. Nevertheless, it can be decreased by enzyme inhibitors such as itraconazole or ritonavir, thus leading to an increase in the bioavailability of ICS. This can result in an accumulation of the steroid drug and a cushing’s syndrome.Case report: We present the case of a 48 year old woman with human immunodeficiency virus (HIV) infection on highly activ...

IntroductionNon-functioning secretory pituitary adenomas are usually characterized by the lack of associated hormone overproduction. The absence of symptoms of excess hormone production results in a delayed diagnosis: sometimes as an incidental diagnosis, sometimes due to compressive symptoms with visual involvement or neurological symptoms as headache. Howewer, hydrocephalus associating Hakim-Adams Syndrome caused by foramen of Monro obstruction seconda...